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Exploring the healing power of poisonous Amazonian frogs 🐸 (KAMBO FROG MEDICINE)
Frog medicine (called kambo), is a healing ritual from the Amazon that involves the poison from the giant Amazonian tree frog. The frog venom is rubbed into small burn marks in the skin. Buy frog medicine online
As the venom enters circulation, it activates the immune and neurological systems — leading to “flu-like” symptoms and the “fight or flight” response.
The session itself is quite unpleasant, leading to nausea, vomiting, sweating, and dizziness. These adverse side effects are actually the goal of the treatment. Buy kambo online
But these effects aren’t all negative — kambo is considered a powerful medicine. It’s used to treat conditions ranging from chronic pain, anxiety, inflammatory disorders, and more.
Does kambo medicine really work? Is it safe?
Here’s everything you need to know about the practice of kambo frog medicine. Order kambo online
GUIDE TO A SAFE KAMBO TRIP
- Check the list of contraindications for kambo
- Find an IAKP accredited kambo practitioner
- Start with a low dose (one dot), & add doses gradually
- Stick to applying treatments on the limbs (not the torso)
- Be cautious of overhydration & water toxicity. Buy kambo frog venom
WHAT IS KAMBO MEDICINE?
Kambo (also called sapo) refers to the poisonous secretions of the giant leaf frog (Phyllomedusa bicolor) from the Amazon rainforest. The secretions are collected and applied to burn marks in the skin. The venom enters the bloodstream through burns made in the skin. Buy kambo medicine in Australia
Usually, practitioners begin with one burn and add up to six burns depending on how the patient responds to the treatment. Kambo frog poison
The frog is well-respected in the Amazon as a powerful medicine — both spiritually and physically. It’s been used for centuries as a panacea for a variety of symptoms and health conditions. Buy kambo medicine in New Zealand
The traditional understanding is that kambo works to “clear blockages” — both energetically and physically.
The modern scientific understanding is that kambo exerts a hormetic response. It triggers the stress response and immune system by essentially “insulting” it — to which the body responds with an even greater defensive action.
The defensive action is what provides the bulk of the long-term benefits of kambo that start to appear a day or two after the ceremony. Buy kambo medicine in Italy
Some describe the benefits as a “recalibration” of the homeostatic mechanisms in the body.
WHAT IS THE DOSE OF KAMBO MEDICINE?
Doses of kambo are measured in “dots” — that is, burn spots on the arm or leg where the kambo venom is administered. Buy kambo medicine in Germany
A single dot delivers roughly 10 mg of venom — however, the quality of the venom used and the diameter and depth of the burn mark (the dot) affect how much kambo venom enters the bloodstream.
A single 10 mg of kambo frog venom contains roughly 320 mcg of caerulein, 220 mcg phyllomedusin,180 mcg of phyllokinin, 30 mcg sauvagine, 53 mcg deltorphins, and 3 mcg dermorphin.
Doses should only be administered periodically — separated by a few weeks or longer. It’s not safe to take kambo medicine on a daily or even weekly basis. Buy kambo medicine in France
THE KAMBO FROG (PHYLLOMEDUSA BICOLOR)
The frog used in kambo medicine is the giant tree frog (also called the monkey frog). It’s found throughout the Amazon rainforest. The only threats to this frog’s existence are the increased interest in its venom as a source of medicine and habitat destruction. At the moment, the frog is widespread and not considered endangered or at-risk.
These frogs are very large, often exceeding 12 cm long (females). The males of this species are smaller, growing up to 10 cm long.
They have a very characteristic look — they’re vibrant green in color with dark spots on the limbs and chest. They also have a distinct “bark” local shamans can pick out in the sea of noise coming from the dense rainforest. Buy kambo medicine in the UK
Interestingly, it’s not known what causes the frog to produce its venom but it’s believed to be sequestered from its environment. Frogs removed from their natural environment won’t produce this venom.
WHAT IS KAMBO MEDICINE USED FOR?
Kambo is not psychedelic and it’s not used to get the user high. In fact, the practice can be quite unpleasant. It makes you feel like you’re sick — resulting in symptoms including vomiting, heavy sweating, rapid heartbeat, muscle aches, and lethargy. Buy kambo medicine in Switzerland
Frog medicine is used as a treatment for a variety of health conditions and there are two camps when it comes to the health benefits of kambo.
There are the more esoteric benefits (supporting motivation and buildup of negative energy), and the physiological effects (antimicrobial action and stress or mood support).
The traditional concept is that the vomiting it induces helps purge the body. Purging is a common method of treatment in traditional medicine around the world. Just about every culture on earth has used or continues to use substances that induce vomiting (emetics) as a source of medicine. Buy kambo medicine in the Netherlands
THE HISTORY OF KAMBO MEDICINE
Purging is used to clear both physical and psychological “buildups.” What these buildups actually involve, depends on the person. Kambo is described as being good for “shaking things up when we’re stuck.” It’s used to improve motivation after low periods in our lives, helping to develop new habits, clear inflammation, and boost energy levels.
Traditional applications of kambo include:
- Enhance a hunter’s precision and acuity before a hunt
- Release of panama (dark or negative energy that accumulates over time)
- Realigning chakras
- Clearing bad luck
- Increase courage, stamina, & strength
- Overcome fear of death or dying
- Removing psychological & emotional “blockages”
- Boosting productivity at work or university
- Clear negative ruminations or toxic mental states
- Managing autoimmune disease of inflammatory conditions
- Treating chronic pain
- Alleviating symptoms of diabetes
- Supporting mood disorders such as anxiety or depression
- To support fibromyalgia or chronic fatigue syndrome
- Eliminate bacterial or fungal infections
- As an adaptogen to buffer our ability to respond to stressful stimuli
WHAT DOES KAMBO FEEL LIKE?
Kambo doesn’t feel great. Within a few seconds of receiving your first dose, you start to feel a burning pain starting at the site of the burn mark which radiates down to your torso. You may begin to feel lightheaded or dizzy, and your heart rate starts to increase. Buy kambo medicine in Greece
It’s common for people to feel anxious or like they’re coming down with the flu.
Eventually, you start to feel overwhelming nausea and dizziness. The room may start to spin and you’ll likely spend a few minutes vomiting into a bucket or making quick trips to the bathroom.
The real benefits of kambo don’t start until a few hours after the experience. Once the effects wear off you’ll begin to feel a new wave of energy. You feel stronger, your mental state feels more clear, and you may even feel a sense of relaxation and wellbeing.
You may notice your skin clear up, your energy levels increase, and you feel a greater sense of wellbeing and mental acuity over the next few days after the treatment. These benefits are reported to remain for 6 months or longer after a single treatment. Buy kambo medicine in Poland
Summary: How Kambo Feels
- Your heart speeds up
- Your throat feels tight
- You may start to feel buzzed or woozy, but it won’t make you high
- You start sweating and getting some muscle shakes
- Your face may become swollen (frog face)
- You feel nauseous and may start to vomit
- You may feel lethargic for an hour or so after
- Overwhelming emotions bubble to the surface
- Your urination increases
- Pain radiates from the source of the treatment to the torso
CAN KAMBO MAKE ME HIGH?
Kambo is not psychedelic and will not make you feel high. It may produce some mild intoxicating effects in higher doses — making users feel woozy, dizzy, or drunk. Buy kambo medicine in Ukraine
Some reports mistake the psychoactive toad venom from the Bufo alvarius toad with kambo.
The bufo toad is found in the Southern United States and Mexico and secretes high concentrations of the intensely psychedelic compound 5-MeO-DMT. The venom is smoked or vaped to produce a profoundly psychedelic experience lasting up to 30 minutes.
The bufo toad venom and kambo frog venom are completely different and can’t be used as substitutes for each other.
The bufo toad is used for spiritual exploration and healing — while kambo is purely used as an alternative medical treatment. Buy kambo medicine in Russia
HOW LONG DOES THE EFFECT OF KAMBO FROG MEDICINE LAST?
Kambo medicine is very short-acting. The effects begin within a few seconds, and peak by the 10-minute mark. The whole process is usually over by about 45 minutes.
In some cases, the effects may linger for longer than this, and it’s common for people to experience fatigue or lethargy for up to 3 hours after the ceremony. Buy kambo medicine in Belgium
KAMBO CEREMONY
The kambo ceremony can vary depending on the practitioner but generally follows the same basic process.
Before the ceremony, participants are asked to fast for about 24 hours. Participants are asked to drink about 1 liter of water or cassava soup prior to attending the ceremony. Sometimes other practices, such as yoga or meditation are also done before the session. Buy kambo medicine in Sweden
When it comes time for the treatment, the practitioner creates a number of small burns with a hot piece of timber on an arm or leg. The blister from the burn is then scraped away to expose the deeper layers where the lymphatic system is located.
The kambo secretions are then rubbed into the burns.
PREPARING FOR KAMBO MEDICINE
Kambo venom can only be extracted from frogs living in the Amazon basin. Frogs raised in captivity don’t secrete the venom.
Frogs are collected from the wild, tied up, and scraped to remove the venom. The frog is not killed in the process and is released back into the wild once the venom is collected. Buy kambo medicine in Austria
The venom is then dried to store for up to a year.
Before a kambo session, the venom needs to be rehydrated by mixing it with some water to make a dark green paste.
HOW MUCH DOES KAMBO COST
Kambo treatments can be expensive. While the practice has been gaining in popularity outside Amazonia over the last few years, it’s still difficult to find a kambo practitioner in most parts of the world. It’s also difficult for practitioners living outside South America to get their hands on a steady supply of kambo frog venom.
All of these factors make the kambo sessions expensive. Buy kambo medicine in Norway
Depending on where you live, the cost for a single session can range from 100EUROS to 400EUROS.
Most practitioners recommend several kambo sessions spaced a few weeks apart. You can usually get a better deal by paying for all of these sessions upfront.
HOW DOES KAMBO MEDICINE WORK?
The active ingredients in kambo frog venom interact with the adrenal, neurological, and immune systems.
Exposure to the venom induces stress-response and activates dozens of cellular survival processes. Compounds in the venom also aggravate the immune system — forcing it to go into overdrive.
The effects are thought to be hormetic in nature — which is a concept where a small trigger can lead to an even larger response and buffering of the system. Buy kambo medicine in Croatia
Exposing the body to stress can lead to a buffering of the stress-response system after the initial insult.
The interaction of kambo medicine with the body is extremely complex.
The neuropeptide receptors kambo medicine work through are still not well understood. They’re involved with regulating just about every cellular function in the body. They’ve been linked with the regulation of our mood, appetite, digestive function, inflammation, pain transmission, immune function, blood pressure, and much more.
This widespread and diverse set of effects is likely the reason why kambo medicine has so many seemingly unrelated benefits. Buy kambo medicine in Denmark
By acting on a central system of neurochemistry, kambo is thought to act like a “reset” for this system. The system is forced into overdrive (temporarily). When the venom wears off, the body is forced to reset, leading to a more idyllic balance of neurochemicals in the body and improved health status.
KAMBO CONSTITUENTS
Many frogs secrete toxic compounds through glands on their back. The poison dart frog, for example, secretes enough venom to kill 10 full-grown humans — despite being no larger than 2 cm long.
Frog venom is used to protect the animal from birds, snakes, and other animals that may seek to eat them. Buy kambo medicine in Romania
The giant leaf frog venom contains well over 100 individual constituents. The most relevant are a group of 16 peptides that interact with various neurological and immune receptors. Many of the active ingredients are classified as tachykinins — which is a large family of neuropeptides (proteins that transmit messages around the neurological system). They’re involved with smooth muscle contraction (blood pressure regulation), intestinal contractions, and various behavioral responses.
The best known naturally-occurring tachykinin in humans is substance P — which is intimately involved in the stress response. It’s used to amplify most cellular processes in the body. Its release leads to inflammation, vasodilation, pain stimulation and inhibition, changes in mood, cellular growth and repair, and the vomiting reflex. Buy kambo medicine in Ireland
Many of the effects of kambo frog medicine are thought to be through similar mechanisms as substance P (NK1, NK2, and NK3 receptor activation).
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There are 16 primary peptides in kambo venom currently being explored in the medical research community:
- Adenoregulin — enhances binding of agonists to the adrenergic (A1) adenosine receptors
- Bombesin — modulates satiety, temperature regulation, glucose homeostasis, and circadian rhythm
- Bombesinnona peptides — thought to have similar effects to bombesin, but not well researched
- Bradykinin derivates — numerous compounds in this group, many with actions on salivary glands & smooth muscle contraction
- Caerulein — stimulates smooth muscle contractions & digestive secretions
- Deltorphin — activate the opiate receptors which provides analgesic effects
- Neurokinin B — a tachykinin involved with temperature regulation & reproduction in women
- Phyllocaerulein — similar structure & effect profile as caerulein on stimulating gastric secretions & smooth muscle contraction
- Phyllokinin — structurally similar to bradykinin but roughly three times stronger
- Phyllolitorin — similar structure & effect profile as bombesin
- Phyllomedusin — classified as a tachykinin and affects the salivary glands, neurokinen receptors, smooth muscle dilation, & tear ducts
- Preprotachykinin B — a tachykinin shown to activate the NK1 or NK2 receptors, causing constriction of the airway
- Ranatachykinin A — activates the substance P receptors & may have pain-reducing effects
- Sauvagine — acts in a similar way to corticotropin releasing factor (binds to CRFR1 & CRFR2) and mimics the physiological reactions to stress
- T-kinin — involved with muscle contraction, particularly in the uterus
- Urechistachykinin II — shown to have antimicrobial action & interaction with substance P receptors
IS KAMBO LEGAL
Kambo is legal throughout most of the world, including the United States and Canada.
Brazil recently banned the practice on a commercial level but allows cultures living in the region to take the medicine as they please. Buy kambo medicine in Finland
Some countries ban the import of kambo venom as a way to slow commercialization of the practice — but allow citizens to use the medicine.
Currently, kambo is not regulated in any country. It’s not considered medicine or food, which means there are no policies or regulations for practitioners using the medicine locally.
This causes some problems.
While kambo is generally regarded as safe, incorrect use can lead to serious harm. People have died from kambo in the past from taking too much or experiencing anaphylactic reactions. Buy kambo medicine in Luxembourg
Regulation is needed to ensure the practitioners administering the medicine are qualified and actually know what they’re doing.
The International Association of Kambo Practitioners (IAKP) has stepped forward as an independent training and accreditation entity to ensure the safe and consistent use of the treatment globally. While it’s not required, I recommend you look for a practitioner that’s been accredited through this association to ensure your experience is as safe as possible. Buy kambo medicine in Czechia
IS KAMBO MEDICINE SAFE?
Whenever working with compounds that trigger the immune system, there’s an inherent level of risk involved. While exceedingly rare, there have been a couple of reported deaths from using kambo. It’s unclear whether these deaths were due to the kambo directly, an interaction of kambo with other drugs or medications, or something else altogether. Buy kambo medicine in Albania
In at least one of the reported deaths the victim had an existing heart condition and took the medication on their own without supervision.
There’s also always a risk of more severe reactions, such as anaphylaxis — which can be life-threatening if not treated immediately.
For this reason, it’s very important you only take kambo with an experienced practitioner. Someone who’s familiar with the safe dose of the venom, knows how to tell the difference between the usual response and something more serious, and how to prepare and administer the venom safely. Buy kambo medicine in Iceland
It’s unclear whether kambo interacts with other drugs or medications or not because there’s never been any official testing.
However, the chances of cross-reaction between kambo and other drugs are very likely. It’s wise to avoid using any other substances before or immediately after receiving a kambo treatment.
It’s also a good idea for people with severe immune-related medical conditions to avoid kambo unless under direct medical supervision. Buy kambo medicine in Malta
SIDE EFFECTS OF KAMBO MEDICINE
- “Frog face” — swelling & edema of the face
- Nausea & vomiting
- Rapid heart rate (tachycardia)
- Heart palpitations
- Lethargy & fatigue
- General sense of malaise and “flu-like” symptoms
ANAPHYLAXIS (Severe Allergic Reaction)
Anaphylaxis is a severe immune reaction to a substance. This is the same response that occurs in people who are deathly allergic to bee stings or peanut butter.
An anaphylactic reaction can happen suddenly — within seconds or minutes. The immune system goes into red alert when exposed to certain compounds, which trigger a severe and over-exaggerated immune response. These changes cause your body to go into shock, which can be life-threatening if not treated with emergency medical care immediately. Buy kambo medicine in Hungary
Signs of anaphylaxis include a closing of the airways (difficulty breathing), rapid heart rate, dizziness, skin rashes, and fainting.
Anaphylactic reactions to kambo are rare, but not unheard of. It’s very important that kambo is applied slowly and deliberately for the first two sessions. This is important to spot signs of anaphylaxis before applying too much kambo. Buy kambo medicine in Cyprus
For many people, it’s the second exposure to a reactive compound that triggers anaphylaxis. For example, many people who are allergic to bee stings only react to the second sting.
Just because your first session didn’t trigger this response, doesn’t mean you’re in the clear yet.
WATER TOXICITY
One of the most common, but overlooked dangers of kambo is drinking too much water.
Water is an important part of the kambo treatment. Before receiving a dose of kambo, participants are asked to fast and drink plenty of water to help with the purge.
But there’s such a thing as too much water. Buy kambo medicine in Bulgaria
Too much water can alter the concentration of electrolytes in the bloodstream — which are critical for muscle function in the heart and arteries. The nervous system also relies on a specific concentration of minerals in the blood to function. If electrolytes become too diluted in the bloodstream from drinking too much water, it can make people feel drunk and may lead to seizures or death.
Kambo places increased risk for water toxicity because it usually involves fasting beforehand, which is then combined with vomiting or diarrhea — all of which can lead to a loss of electrolytes. Secondly, the increased intake of water further dilutes the electrolytes.
It’s important that the kambo practitioner administering the medicine knows what the signs of water toxicity are and has access to emergency electrolyte drinks or powder to avoid any serious issues. Buy kambo medicine in Slovenia
MISIDENTIFICATION OF THE KAMBO FROG
It’s possible for the person collecting the frog to mistakenly harvest the venom from the wrong frog. Some Amazonian frogs contain much more toxic venom that can cause serious illness or death if applied during a kambo medicine ceremony. There have been past reports of people mistakenly using the venom from toads in the Chaunus genus — such as the toxic cane toad Rhinella spp. or psychedelic Bufo alvarius toad.
The only venom that should ever be used in the kambo ceremony is the venom obtained from the giant tree frog (Phyllomedusa bicolor).
There have been reports of people smoking, eating, or snorting the kambo frog venom — which leads to a set of incurable symptoms that gradually develop referred to as “frog disease.” Buy kambo medicine in Estonia
There are only a few older anecdotal reports available about the syndrome, which reportedly causes users to feel like their “brain is being eaten. The muscles become weak and cardiac arrest can occur (lethal). It’s thought these effects arise from parasites present in some frog venom samples. These effects have not been reported by users taking the venom in the traditional method through burns. It’s thought these parasites are killed by immune responses generated at the site of the burns. Buy kambo medicine in Serbia
WHEN TO AVOID KAMBO MEDICINE
Kambo medicine isn’t appropriate for everybody.
Certain medical conditions or prescription drug use can make the treatment riskier than it’s worth, including:
- People diagnosed with a heart condition or have had heart surgery
- People who have a history of stroke
- People with blood clotting disorders
- Anybody still recovering from a recent surgical procedure
- People taking medications to control low blood pressure or severe hypotensive disorders like Shy-Drager
- People with severe hypertension
- People with psychiatric disorders like schizophrenia or psychosis
- People currently undergoing chemotherapy or radiotherapy
- People who have had a recent organ transplant
- Anybody using immunosuppressants
- People with epilepsy or seizure disorders
- Anybody under the age of 18
- Pregnant or breastfeeding women
KAMBO MEDICINE RESEARCH
Research on kambo began back in the 1960s but hasn’t yielded any new medications despite some promising findings. It’s been difficult for researchers to gain patents to develop profitable medications from kambo. Buy kambo medicine in Slovakia
More recently there’s been a growing interest in the potential for new drug discovery in the kambo frog venom. There’s been a lot of published research on potential medical applications of the venom over the last couple of years, with more papers published every year.
Here’s a summary of the current medical research on kambo frog medicine.
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One of the compounds in kambo frog venom, dermaseptin B2, has been shown to inhibit certain types of cancer cells (human prostatic adenocarcinoma) by more than 90%. It works by causing cell death (necrosis, not apoptosis) in cancer cells. Kambo medicine for sale
Neuroprotective Effects
Active ingredients in kambo frog venom such as adenoregulin have been shown to bind to adenosine receptors in the brain, which is involved with the permeability of the blood brain barrier. It’s currently being explored as a potential treatment for conditions like Alzheimer’s disease, Parkinson’s disease, depression, strokes, and more due to this effect. Buy kambo medicine in Scotland
Antimicrobial Effects
Various dermaseptins in kambo frog medicine have been shown to produce powerful antimicrobial actions in various in vitro studies. They’ve been shown to provide exceptional antiparasitic and antibacterial actions without damaging mammalian cells. Buy kambo medicine in England
This makes kambo frog venom a promising candidate for the development of new antimicrobial substances.
The ability for these compounds to cross the blood-brain barrier makes them especially interesting as a source of antimicrobial treatment. There aren’t many medicines currently available for treating infections beyond the blood-brain barrier. Buy kambo medicine in UAE
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(Kampo, Sapo, Vacina do sapo, Medicina da floresta, Frog medicine)
Kambo, also known as frog medicine, is the venomous secretion of Phyllomedusa bicolor (the giant leaf or monkey frog), a bright green tree frog native to the Amazon basin. It can be found in the Amazon rainforests of South America in the regions of northern Brazil, eastern Peru, southeastern Colombia, and parts of Venezuela, Bolivia, and the Guianas. In many regions outside Brazil, both the frog and its secretion are known as sapo (or ‘toad’). Buy kambo medicine in USA
Giant monkey frogs have a distinctive “song” that can be followed to collect them at night. Captive specimens are tied by the legs stressed to induce the secretion: a waxy substance scraped onto wooden splinters from the back and legs of the frog. Dried kambo can be stored for upwards of a year without losing its potency. For use, it’s mixed with saliva or water and directly applied to specially made skin burns. Buy kambo medicine in Canada
As the popularity of kambo has grown, so has concern over how these harvesting methods will affect the species. While the frogs are not killed when the secretions are harvested and the giant monkey frog population is currently listed as stable, this practice has come under scrutiny for how the animals are treated. Buy dried kambo medicine
Kambo has a range of traditional and potential therapeutic applications, both medical and psycho-spiritual. Commonly described as an ‘ordeal medicine’, the frog secretion is known for its powerful emetic or purgative effects. Despite its initial unpleasantness, kambo is widely sought out to revitalize body and mind. Where can i buy dried kambo venom
The word “Kambo” often refers to both the substance and the ceremony. The two are fundamentally linked, and each provides the context and purpose for the other. To understand Kambo, one must understand the Kambo ceremony.
Some substances deliver euphoria. They make you laugh; they make you see things. People bring them along on hikes, to concerts, to parties, and let them run their course in all sorts of different environments. Dried kambo medicine
Kambo is no such substance. Kambo is frog poison, and it makes you feel uncomfortable. People don’t take Kambo to have fun, but to purge, cleanse, and heal themselves.
The Kambo ceremony accounts for the discomfort and is structured to provide a safe setting for a challenging experience. People participate in Kambo knowing what awaits. There are no distractions from the experience because, with Kambo, there shouldn’t be. It’s a common saying that Kambo gives you what you need, but not what you want. In this sense, Kambo is both frog poison and frog medicine.
A BRIEF NOTE ON KAMBO ETHICAL PRACTICES
There’s a growing concern surrounding the ethics and sustainability of harvesting and exporting Kambo from giant monkey frogs. As detailed below in the section on sustainability, many Kambo alternatives are available and readily accessible to those not residing in areas where the frog populations are found. Buy kambo medicine in Latvia
If you still absolutely feel the call to use Kambo, we recommend finding a center in an area where the giant monkey frog resides naturally and putting in the effort to ensure that the Kambo used is sourced ethically and sustainably.
Some harvesting practices require the frog’s limbs to be tied while the animal is subjected to stressful stimuli to induce secretion. Others say the frog will only secrete its venom if the practitioner has good intentions. Whatever your beliefs, be aware of the methods and practices that go into your Kambo experience.
KAMBO CEREMONY IN AUSTRALIA
Preparations are useful for any potentially transformative, substance-induced experience. When taking Kambo, they are necessary. Mostly these preparations relate to the purging and cleansing that occurs during the ceremony.
The cleansing process begins before the actual ceremony. Most Kambo practitioners recommend fasting for 10-12 hours before use. Recreational drugs and alcohol are also prohibited for at least 24 hours prior. Finally, those taking Kambo should aim to drink at least 1-2 liters of water before the ceremony. These steps make the eventual purging easier.
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To prepare Kambo, the dried resin is combined with a little water or saliva to form a paste-like “green mustard.” It is then divided into dots for application. Small points (roughly 1/8” in diameter) are burned through the top layer of the skin with a smoldering piece of titica vine (Heteropsis flexuosa), a twig, or an incense stick. Once the skin has been removed from the burns—as painlessly as from a blister—the Kambo dots are applied. Aided by Kambo’s vaso dilating peptides and pro-inflammatory agents, they are absorbed into the bloodstream within seconds.
Usually, a large quantity of liquid is consumed beforehand—for example, two liters of water, 3-5 liters of fermented corn caiçuma, a manioc or banana gruel, or diluted papaya juice. However, due to the health risks of hyponatremia, we would not recommend drinking large quantities of liquid in a short space of time.
According to Peter Gorman, the normal dosage is roughly 10 mg of Kambo for each point, up to a maximum of 100 mg per day. The number of points varies depending on body size, experience, reasons for application, and sometimes the practitioner’s tradition. While five points appears to be common, considerably more or less may be required.
THE KAMBO CEREMONY AND EXPERIENCE
Group Kambo ceremonies usually have 10 or fewer participants. Apart from the practitioner, there may also be assistants. The assistants have multiple roles to play. They might bring out buckets when someone is ready to purge or escort someone who needs to go to the restroom. Sometimes, they may merely act as a calm and supportive presence.
The practitioner applies the Kambo to participants, using small burns made on the skin. Also known as “gates,” these burns allow the pasty substance to enter the bloodstream quickly. These gates can leave scars, though they can fade with time and care. Practitioners sometimes also apply oils and balms to reduce scarring after the ceremony.
Often, a test point will be used first to determine if the participant experiences any adverse effects. Once it is deemed safe for use, the shaman or practitioner will begin the application. Practitioners measure Kambo in “points,” and anywhere from 2 to 10 points may be applied.
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The immediate effects of Kambo medicine are intense and unpleasant but short-lived, usually lasting no more than 30-40 minutes. They include a feverish rise in temperature, sweating, shivers, and dizziness as the heart rate becomes rapid—possibly reaching more than 190 beats per minute. The blood pressure may rise or fall dramatically, accompanied by increased awareness of the veins and arteries. Many people report a tingling or burning sensation like electricity that starts from the points and spreads through the body. Some may also feel a dissociative or drunken high.
Overwhelming nausea is generally unavoidable with Kambo and purging is likely—either by vomiting, defecation, or both. Other effects include a feeling of pressure in the head, neck, and torso, stomach pain, inflammation of the throat, dry mouth, blurred vision (or temporary blindness), difficulty moving, and numb, swollen lips and tongue. This is the body’s physical reaction to acute poisoning.
After these initial biological effects have worn off and the heart rate has returned to normal, it may be necessary to rest. Some fall into a dreamless sleep, while others make strange animal noises.
Your experience may feel enhanced following the Kambo purge. You may feel great physical strength, sharpened senses, and heightened mental alertness. Desirable after-effects like these may take a day to materialize or they could be immediate. They also tend to include a consistently elevated mood, increased physical and mental energy, decreased stress, and enhanced focus.
PRECAUTIONS BEFORE TAKING KAMBO
Kambo is best taken on an empty stomach, bladder, and bowels. It’s advisable to avoid solid food, and especially salt, for 8-10 hours beforehand. Alcohol should also be avoided for 24-48 hours before application.
It’s a good idea to test a small amount of Kambo on the skin before administering it to burns. Many practitioners wait up to a day to gauge negative reactions. It is highly advised not to try this on your own, but to find an experienced Kambo-giver or guide, due to the possibility of adverse effects or medical contraindications that could have severe or fatal consequences. At the bare minimum, if self-administering Kambo, a sitter is necessary. Also, keep in mind that Kambo could be habit-forming. 12 applications per year is a good upper limit.
Kambo is frequently offered alongside ayahuasca, ibogaine, 5-MeO-DMT, and other plant medicines for holistic treatment. According to practitioners, the skin secretions “resets” the body, not only by strengthening the immune system but also through distinct psycho-spiritual benefits.
Panema—an Arawak term used by the Ashaninka and others—describes a negative energy that gathers over time. Traditionally visualized as a kind of dense grey cloud or aura, panema is blamed for bad luck, depression, laziness, irritation, and other adverse states. Naturally, clearing this cloud is vital for indigenous groups that depend on hunting and community coherence. For many, kambo serves this purpose.
Outside of traditional contexts, the dissipation of panema is framed in terms of “clearing the pain body,” “realigning the chakras,” or reorganizing personal psychology. The purge itself may be felt as an expulsion of bad thoughts, habits, negative personality traits, or persistent life problems.
A profoundly transformational tool, kambo medicine is known to increase compassion, courage, emotional stability, and personal sovereignty. Some users feel more “real” or “solid” after kambo application—less in their heads and more in their bodies. Frustration, anger, and anxiety also tend to reduce or dissipate entirely. These positive changes may last several days or several months, depending on the application and the person receiving it.
Kambo may also help to overcome a fear of dying. According to one practitioner, terminally ill patients have claimed to see “the other side” during their experience, returning with a newfound serenity about death.
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One of kambo’s most exciting potential medical applications is the treatment of cancer. Dermaseptin B2 has been shown to inhibit cancer cell (human prostatic adenocarcinoma) growth by more than 90%. This peptide penetrates cells and works by necrosis (active destruction) and not apoptosis (normal or programmed cell death).
Dermaseptins, including adenoregulin, are powerful antibiotics. Found to be rapidly and irreversibly effective against a range of parasitic microorganisms, they’re also entirely non-toxic to mammalian cells. Combined with their ability to cross the blood-brain barrier, peptides in kambo are especially promising for conditions like Cryptococcal meningitis in patients with late-stage HIV. Among the pathogens killed by dermaseptin B2 are the filamentous fungi that opportunistically infect AIDS patients. With the emergence and spread of highly resistant pathogenic bacteria, novel antibiotics such as these are becoming critical.
Since adenoregulin affects the binding of agonists to adenosine receptors—instrumental in the permeability of the blood-brain barrier—it may be useful in the development of treatments for Alzheimer’s disease, depression, and strokes. Anecdotal evidence supports kambo’s use in depression treatment, anxiety, and addiction.
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There’s also compelling anecdotal evidence for kambo’s effectiveness in the treatment of chronic fatigue syndrome (CFS). According to one sufferer, the secretion completely eliminates CFS symptoms when taken regularly.
The deltorphins and dermorphin present in kambo have analgesic effects comparable to the body’s own pain response of beta-endorphin release. They’re also stronger than morphine without the same level of respiratory depression, tolerance potential, and withdrawal symptoms.
Phyllokinin may be useful in the treatment of hypertension, having been shown to lower blood pressure more effectively than other polypeptides.
Other conditions that may benefit from kambo include chronic pain, Parkinson’s disease, vascular problems, hepatitis, diabetes, rheumatism, and arthritis.
Kambo is legal in the United States and most, if not all, other countries. The only restriction appears to be the Brazilian government’s 2004 ban on kambo’s commercialization.
Vittorio Erspamer described the Phyllomedusa genus as a “treasure trove” of bioactive peptides—short chains of amino acids that bind to human cell receptors. The frog Phyllomedusa bicolor skin secretion particular contains dozens of peptides, most significantly including phyllocaerulein, phyllomedusin, phyllokinin, sauvagine, dermaseptin B2, adenoregulin, deltorphins, and dermorphin. KAMBO FROG MEDICINE
RECEPTOR BINDING
Phyllocaerulein is a hypotensive neuropeptide that stimulates the adrenal cortex and pituitary gland. Present in kambo at around 32 micrograms per milligram, it has a role in the medicine’s analgesic and satiety effects.
Phyllomedusin interacts with tachykinin receptors—shown to regulate the functions of dopamine, serotonin, and other neurotransmitters—while phyllokinin targets the bradykinin receptors. Phyllomedusin contracts smooth muscles while phyllokinin relaxes them. Both are potent vasodilators, increasing the permeability of the blood-brain barrier. They are present in kambo at around 22 and 18 micrograms per milligram, respectively. KAMBO FROG MEDICINE
Sauvagine, present at 3 micrograms per milligram, functions like a hormone. It interacts with the pituitary-adrenal axis and corticotropin-releasing receptors—involved in stress, anxiety, depression, and addictive behavior.
Adenoregulin stimulates the binding of agonists to A1 adenosine receptors and is shown to cause behavioral depression in mice.
Deltorphins and dermorphin are both powerful opioid receptor agonists. Deltorphins in particular have among the highest binding affinity and selectivity to delta opioid receptors of any natural compound. Dermorphin is highly selective for mu opioid receptors. Present at 5.2 and 0.25-0.33 micrograms per milligram, respectively, these peptides are many times more potent than endogenous beta-endorphin. KAMBO FROG MEDICINE
SAFETY AND TOXICITY
Little is known about the long-term safety of kambo and the potential health risks, but evidence suggests that deltorphin and dermorphin may cause respiratory depression and lead to heavy reliance with frequent use. Kambo-related deaths have also been linked to the secretion’s depressive effects on the central nervous system. Toxins present in kambo may affect the cardiovascular system, kidneys, pancreas, and liver. In one case, it led to toxic hepatitis caused by the frog secretions. KAMBO FROG MEDICINE
The International Association of Kambo Practitioners (IAKP) insists that sudden death is rare and almost always attributable to some pre-existing condition. Common contraindications include hyper- or hypotension, brain hemorrhage, aneurysm or blood clots, Addison’s disease, epilepsy, heart problems, and pregnancy.
Anecdotal reports warn of “frog disease,” an incurable condition arising from the non-traditional use of kambo (e.g. oral consumption, smoking, or insufflation). Apparently inducing a feeling of your brain being eaten, “frog disease” is characterized by weak muscles, cardiac arrest, and death. The condition may be caused by parasitic microorganisms—usually eliminated by the body’s immune response to skin burns.
Kambo is supposedly named for the legendary pajé (or medicine man) Kampu. This ancestral shaman is said to have learned about the medicine from a forest spirit, having exhausted all other means to heal his sickly tribe. According to the Kaxinawá, the spirit of Kampu lives on in the giant monkey frog, continuing to heal any who seek it.
Whatever the mythical origin, kambo medicine has long been used by indigenous Pano-speaking groups in the Amazon, including the Katukina, Asháninka, Yaminawá, and Matsés (or Mayoruna). It may also have been used by the classical Maya, whose art depicted tree frogs next to mushrooms. Traditional uses include eliminating toxins, increasing strength and stamina, monitoring pregnancy (or inducing abortion), and dispersing negative energy, or panema. In the rainforest, kambo is used within shamanic hunting practices and as an aid, reducing the need for food and water and minimizing the human scent. Fortified by the “vaccine,” hunters are also thought to emit a strange green light that draws their prey near. KAMBO FROG MEDICINE
The first Westerner to witness kambo use in the Amazon was the French missionary Constantin Tastevin, who stayed with the Kaxinawá in 1925. According to his informants, the kambo ritual of self-envenomation originated with the neighboring Yaminawá.
KAMBO CEREMONIA
Kambo was rediscovered in the 1980s by journalist Peter Gorman and anthropologist Katharine Milton —both of whom spent time living with the Matsés/Mayoruna of northeastern Peru/southwestern Brazil. They each supplied kambo samples to the biochemists John Daly and Vittorio Erspamer , who analyzed the secretion’s peptide content and saw great medical potential. Pharmaceutical companies have made efforts to synthesize and patent kambo peptides, but have largely struggled to develop medications. KAMBO FROG MEDICINE
Until 1994, kambo was rarely applied to non-Indians. It was first offered as a therapy by Francisco Gomes, a half-Katukina caboclo living in São Paulo. From around 1999, he was joined by Santo Daime practitioner and acupuncturist Sonia Maria Valença Menezes and other non-Indian kambo applicators, including holistic therapists, doctors, and members of the União do Vegetal religion.
In 2004, the Brazilian government prohibited all advertising of kambo’s medical or therapeutic benefits, effectively shutting down the new urban applicators. In part, this was a legal response to the Katukina’s demand to protect their ‘intellectual property’. KAMBO FROG MEDICINE
CURRENT USE
There’s some concern within the kambo community that commercial supply chains might exploit indigenous tribes. Bulk production of kambo sticks could also pose a threat to P. bicolor populations in the wild.
Kambo and the Sustainability of the Giant Leaf Frog
The giant leaf frog population is currently listed as stable, but the explosion in kambo’s popularity increases future risk for the species. With the increase in demand, some locals are incentivized to capture and sell the frogs, removing them from their original habitat and putting pressure on an ecologically sensitive species. And while “Kambo sticks” can be purchased online, it’s often difficult to be sure of the source origin and how it was procured. KAMBO FROG MEDICINE
Furthermore, methods of inducing secretions can be stressful to the frogs, which could have adverse effects on their survival. The animals are typically restrained by tying their limbs and spreading them out in an X shape while secretions are scraped off their skin. Methods of inducing venom exposure so the secretion can be harvested involve exposing the frog to an open flame or physical, non-lethal blunt trauma.
While other, less invasive methods can be used to harvest their venom, the frogs do undergo some level of stress and trauma prior to being released. Some practitioners, on the other hand, argue that the frog only provides venom when the person harvesting it has good intentions, but this is debated in the community. Regardless, scaling up venom harvesting practices to meet demand will only increase population-wide stressors on the species and it’s unclear how well they can cope.
Cultural Appropriation of Kambo
Kambo has been used by indigenous peoples in the Amazon for possibly thousands of years. Small scale, local use in areas where few alternatives exist can be defended from both a practical and ethical viewpoint. But with the surge in demand all over the world, some have criticized use outside of these contexts as cultural appropriation.
For example, it’s become somewhat of a badge of honor in online communities to post images of skin burn marks after using kambo. While these users might genuinely be seeking the healing properties of kambo, this practice is considered to be far removed from the original context of the medicine’s purpose.
Most westerners have access to more sustainable and less culturally sensitive alternatives for many ailments. Here are just few examples: KAMBO FROG MEDICINE
- Psilocybin and ketamine have shown remarkable promise in treating depression.
- Ayahuasca and ibogaine have proved effective in treating alcoholism and many other addictions.
- Cannabis, CBD, kratom, ketamine, and even microdoses of LSD can be used to help manage pain.
- Many plant sources are available for emetic and purgative purposes as well (such as ayahuasca)
“Kambo is hallucinogenic”
P. bicolor is occasionally referred to as an “hallucinogenic tree frog”, with some users reporting visions of varying intensity. However, none of the peptides present in kambo are known to produce these effects. Hallucinations are far more likely due to other, psychoactive substances that are commonly taken with kambo, such as nu-nu snuff.
Can it be detected in a drug test?
Peptides are notoriously difficult to test for. Dermorphin, known for postoperative pain, for instance, which has become an illicit performance enhancer for racehorses, can only be detected by specialist labs. Although kambo contains opioid receptor agonists, it doesn’t contain any opiates. It is therefore extremely unlikely to be detected in a drug test.
Can kambo cause psychological trauma?
The unpleasant effects of kambo can feel endless for those experiencing them. There may also be a feeling of drunkenness or dissociation. For the most part, however, kambo is not psychoactive.
Are there risks?
Kambo is relatively safe when properly applied to healthy individuals. However, it is likely unsafe for children, pregnant or breastfeeding women, people with heart problems, and patients either recovering from surgery or taking immuno-suppressants for organ transplant. It should also be avoided by chemo- and radiotherapy patients, including those planning to start treatment within four weeks.
Will kambo leave scars?
Yes—although kambo scars fade over time, they won’t disappear completely. Aftercare balms such as sangre de drago may help to improve their appearance. Alternatively, the same points can be used within 2-3 months of the previous application. KAMBO FROG MEDICINE
Can I keep the kambo frogs at home?
P. bicolor can be kept as pets, but they’re not an amphibian for beginners. Captive specimens also don’t appear to secrete the same kind of venom as those in the wild—possibly due to dietary differences.
What is the safest way to take kambo?
The only safe way to administer kambo appears to be via skin burns, but the specifics tend to vary between practitioners. In the caboclo kambo initiation, for instance, the medicine is traditionally applied at the new moon of three consecutive months—each time increasing in dosage. Kambo may also be double- or triple-dosed within a single session. KAMBO FROG MEDICINE
Can I use kambo to microdose?
There’s very little information on microdosing with kambo, but some consider it dangerous. Purging (i.e. with large doses) is thought essential for releasing toxins.
Does it produce kambo tolerance?
Frequent users build up a tolerance to kambo. Some Katukina men take more than 100 points at a time. Anecdotal reports suggest that sananga and ibogaine can reverse the tolerance effect.
Can I mix kambo with other drugs?
Kambo is often used in conjunction with ayahuasca because advance purging helps to optimize absorption. The vasodilating peptides phyllomedusin and phyllokinin also serve to increase the permeability of the blood-brain barrier.
Kambo may also be taken with certain psychoactive snuffs, including nu-nu and rapé, as well as ibogaine.
The safety of combining kambo with other substances is not entirely known, but alcohol should be avoided. It’s also recommended to avoid recreational drugs for at least three days after kambo has been applied.
IN CONCLUSION: WHAT IS KAMBO?
Kambo medicine, also called sapo or frog medicine is an alternative medical treatment involving the application of poisonous tree frog venom into burns on the skin. The practice was invented in the Amazon rainforest where the frog lives. It’s used as a purgative to clear blockages in the body and treat a long list of medical conditions.
The modern medical understanding of kambo medicine sees it as a hormetic medicine. It triggers core biological responses by aggravating them with small doses of the poison — to which the body responds with an even stronger defensive action.
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